"Registry-based non-randomized studies for treatment comparisons"
Symposium
The project NANA team from the Department of Medical Statistics, University Medical Center Göttingen, is pleased to announce a symposium on current methods for registry-based non-randomized studies for assessing the benefits and harms of drugs and other medical interventions to support decision making (e.g., regulatory and Health Technology Assessment).
The symposium has been held on 26th of May 2026 from 11 am – 5 pm in Göttingen.
We discussed insights and results from the NANA project and invited speakers shared their experiences and innovative methodological approaches at the intersection of statistics, data requirements, and regulatory requirements.
Find here the symposium programme as PDF.
Programme and download of presentations
- 11.00am - Arrival
- 11.30am - Welcome
Tim Friede (Department of Medical Statistics, UMG, Göttingen) - 11.40am - Design and Methods for Comparative Non-randomized Studies
Uwe Siebert (UMIT TIROL) - 12.10pm - Non-Randomized Studies for treatment comparisons using German Registry Data: Insights from the NANA Project [PDF]
Paula Starke, Malik Enes Cakir, Maxi Schulz (Department of Medical Statistics, UMG, Göttingen) - 1.00pm - Light lunch
- 1.45pm - Target trial emulation and the importance of alignment at time zero: some examples using health claims data [PDF]
Vanessa Didelez (BIPS, University of Bremen) - 2.15pm - Using routinely collected data for research purposes: Challenges and mitigation strategies [PDF]
Sabine Hoffmann (LMU Munich) - 2.45pm - Achieving interpretable machine learning by functional decomposition of black-box models into explainable predictor effects [PDF]
Matthias Schmid (University of Bonn) - 3.15pm - Coffee break
- 3.30pm - Registry-based non-randomized studies in benefit assessments [PPTX]
Volker Vervölgyi (IQWiG) - 4.00pm - Regulatory pathways and deviations from the gold standard RCT – a reflection on data from non-randomized studies in drug approval [PDF]
Lukas Aguirre Dávila (Paul-Ehrlich-Institut) - 4.15pm - Panel discussion: When and how can non-randomized studies contribute robust real-world evidence? Aligning methods, data, and regulatory standards.
- 4.50pm - Closing remarks and farewell
Tim Friede (Department of Medical Statistics, UMG, Göttingen) - 5.00pm - End of symposium
Venue
Tagungszentrum an der Sternwarte
Großer Seminarraum
Geismar Landstr. 11b
37083 Göttingen