Symposium Translational Studies

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"Statistical Planning of Translational Studies"

Symposium

A symposium on current methods for statistical planning of translational studies has been held on 20 MAR and 21 MAR 2024 in Göttingen, led by Tim Friede and Frank Konietschke.

The symposium is part of the joint research project "Statistical Planning of Translational Research" of Tim Friede and Frank Konietschke, funded by the German Research Foundation (DFG).

Impressions from the symposium

Poster session with "Wine and Cheese Reception"

Programme and Download of Presentations

Wednesday, March 20th 2024 (1:30pm - 6:30pm)

1:30pm - 1:35pm - Welcome
Tim Friede (University Medical Center Göttingen)
Frank Konietschke (Charité – Universitätsmedizin Berlin)
1:35pm - 2:20pm - "Group sequential designs and sample size re-estimation" [PDF]
Christopher Jennison - Keynote (University of Bath)
2:20pm - 2:40pm - "Sample size re-estimation in nonparametric models"
Stephen Schüürhuis (Charité – Universitätsmedizin Berlin)
2:40pm - 3:00pm - "The studentized permutation test in group sequential designs" [PDF]
Long-Hao Xu (University Medical Center Göttingen)
3:00pm - 3:40pm - Coffee break
3:40pm - 4:25pm - "How to benefit from statistics in toxicology and the added value of high-dimensional data" [PDF]
Jörg Rahnenführer - Keynote (TU Dortmund University)
4:25pm - 5:00pm - "The use of (historical) control data in toxicology" [PDF]
Max Menssen (Leibniz Universität Hannover)
5:00pm - 5:25pm - "The use of historical control data in clinical trials" [PDF]
Christian Röver (University Medical Center Göttingen)
5:25pm - 6:30pm - Poster session with "Wine and Cheese Reception"

Social Programme:

7:00pm - Joint dinner at the "Kartoffelhaus" restaurant
Self-pay for symposium attendees. If you would like to attend the dinner, please contact Judith Heinz by 3 March 2024 at the latest.

Thursday, March 21st 2024 (9:00am - 1:00pm)

9:00am - 9:10am - Welcome
Tim Friede (University Medical Center Göttingen)
Frank Konietschke (Charité – Universitätsmedizin Berlin)
9:10am - 9:55am - "Guiding phase I dose escalation for modern cancer therapies – recent developments, opportunities and challenges" [PDF]
Lukas Widmer - Keynote (Novartis Basel)
9:55am -10:10am - "Bootstrap tests and confidence intervals for a Hazard Ratio when the number of observed failures is small, with applications to group sequential survival studies" [PDF]
Christopher Jennison (University of Bath)
10:10am - 10:30am - "Sample size calculation and recalculation for non-inferiority trials in the 'gold standard' design with heterogeneous variances" [PPTX]
Maxi Schulz (University Medical Center Göttingen)
10:30am - 10:50am - "Multiple contrast tests for count data"
Mareen Pigorsch (Charité – Universitätsmedizin Berlin)
10:50am - 11:30am - Coffee break
11:30am - 11:50am - "Sample size planning for multiple contrast tests"
Anna Pöhlmann (Charité – Universitätsmedizin Berlin)
11:50am - 12:10pm - "Sample size planning for the Wilcoxon-Mann-Whitney test with clustered data" [PDF]
Erin Sprünken (Charité – Universitätsmedizin Berlin)
12:10pm - 12:30pm - "A maximum Wilcoxon-Mann-Whitney test for high-dimensional data" [PDF]
Lukas Mödl (Charité – Universitätsmedizin Berlin)
12:30pm - 1:00pm - Discussion moderated by Tim Friede/Frank Konietschke
1:00pm - Farewell

Registration

Registration is free but required by 3 March 2024 at the latest.
For registration please contact Judith Heinz at judith.heinz(at)med.uni-goettingen.de.