Scientific Core Facility Medical Biometry and Statistical Bioinformatics

Department of Medical Statistics

The Scientific Core Facility Medical Biometry and Statistical Bioinformatics (MBSB), situated at the Department of Medical Statistics, is an infrastructure unit of the University Medical Center Göttingen. It is tasked with biostatistical and bioinformatics support for the institutions, working groups and doctoral students of UMG in the planning and analysis phase of their studies and experiments.

Bioinformatics support comprises the analysis of microarray, proteomics as well as next-generation sequencing (NGS) data in particular. Depending on current capacity, these services can also be used by other institutions of Georg August University of Göttingen, as well as other research facilities within the Göttingen Research Campus.

On this website you will find an overview of our service portfolio as well as contact information. You may also refer to out terms of service  as well as our fees catalog.

Due to the Covid-19 pandemic, our consultation services as well as coached working will be conducted online at the moment.

Services offered

[Translate to Englisch:] Nahaufnahme eines Quellcodes am Monitor

MBSB offers support for the following:

  • Study design, sample size calculations
  • Biostatistics and bioinformatics approaches for grant applications
  • Data wrangling, data management
  • Statistical analysis of medical and biological datasets
  • Bioinformatics analysis of medical and biological datasets (e.g. microarray, proteomics and next-generation sequencing data)
  • Analysis of sequencing data (e.g. RNA-seq, ChIP-seq, Methyl-seq, metagenomics Data, copy number changes)
  • Development of specialized analysis approaches and software
  • Interpretation of results
  • Software selection
  • Visualization and representation of results

Short consulting

Short consulting is mainly targeted at doctoral students with questions regarding statistical and bioinformatics matters in their dissertation, as well as other researchers. Office hours are Tuesdays 1-3pm, and can be attended as often as required. To avoid long waiting times, sessions are typically limited to 15-30 minutes. No prior appointment is necessary.

Due to the Covid-19 pandemic, consultations are via video conference only. Please visit the waiting area in RocketChat to participate.

Professional analysis and study design

We offer professional biostatistics and bioinformatics design and analysis for scientific studies. We recommend to contact MBSB early on, i.e. in the planning phase of the experiment, to ensure an appropriate match between the study goals, its design, data collection and analysis. This helps to avoid serious flaws which could jeopardize the study.

Registration

To register for an appointment, please use our PDF or web form. A staff scientist will contact you shortly afterwards for a date and time. Please note that, depending on the extent of the research, this service may involve a fee. This money serves only to re-finance the core facility and will be fully rerouted back into the UMG research budget.

Coached working

During coached working, we offer support in the use of statistics and bioinformatics software such as Statistica, SPSS, SAS and R. This service is on a drop-in basis and does not require previous registration.

For more information, please visit the website.

Methods and software courses

MBSB offers special courses for selected biostatistics and bioinformatics methods and software. Dates will be announced on our website as well as by our newsletter. Examples include:

  • „Data Analysis in Proteomics“
  • „Biometry und sample size planning in grants for animal studies“
  • „Analysis of NGS experiments“

Registration

Details will be provided with the respective course announcement.

Contact

Head

Dr. Andreas Leha

contact information

Research Associate

Dr. John Wiedenhöft

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Wissenschaftlicher Mitarbeiter

Dr. Fabian Kück

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